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Xenical orlistat or alli, while another study conducted by the American Diabetes Association found that a low-carb diet significantly reduced the risk of heart attack (5). Advertisement We found two studies that specifically looked at the relationship between weight-loss efforts and insulin levels. One study, by the American Association of Diabetes Educators America, examined the relationship between weight-loss efforts and insulin levels found that the more time subjects lost weight, the lower insulin levels. This supports previous research that has found people who have a high amount of calories, whether from carbs or not, tend to have higher insulin levels. The study found that subjects who had low fasting insulin levels—those who did not need insulin in the fasting state to process carbohydrates—were able lose more weight and have less risk of developing diabetes than their high-fiber-carbohydrates-fed counterparts. The second study looked at a group of 1,250 people who either had high carbohydrate intake or low intake; this group lost more weight overall, but also had higher weight loss at the end of study. As study authors explained, high carbohydrate intake (defined as "high consumption of breads and cakes in a meal") can result higher body weight, insulin production, and higher resistance. However, low carbohydrate intake (defined as "low Xenical